Zhang, K., et al., The non-toxigenic Clostridium difficile CD37 protects mice against infection with a BI/NAP1/027 type of C. difficile strain. Anaerobe, 2015. 36: p. 49-52.


Wang, Y.-K., et al., A chimeric protein comprising the glucosyltransferase and cysteine proteinase domains of toxin B and the receptor binding domain of toxin A induces protective immunity against Clostridium difficile infection in mice and hamsters. Human Vaccines & Immunotherapeutics, 2015. 11(9): p. 2215-2222.


Yong, Y., et al., Identification and functional characterization of Toll-like receptor 2–1 in geese. BMC Veterinary Research, 2015. 11: p. 108.


Huang, T., et al., Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells. Pathogens and Disease, 2015. 73(3): p. ftv008.


Wang, Y.-K., et al., Screening of Single-Stranded DNA (ssDNA) Aptamers against a Zearalenone Monoclonal Antibody and Development of a ssDNA-Based Enzyme-Linked Oligonucleotide Assay for Determination of Zearalenone in Corn. Journal of Agricultural and Food Chemistry, 2015. 63(1): p. 136-141.


Sponseller, J.K., et al., Hyperimmune Bovine Colostrum as a Novel Therapy to Combat Clostridium difficile Infection. The Journal of Infectious Diseases, 2015. 211(8): p. 1334-1341.


Sun, X. and S.A. Hirota, The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection. Molecular immunology, 2015. 63(2): p. 193-202.


Peng, Z., et al., Antibiotic Resistance and Toxin Production of Clostridium difficile Isolates from the Hospitalized Patients in a Large Hospital in Florida. Frontiers in Microbiology, 2017. 8: p. 2584.

Peng, Z., et al., Update on Antimicrobial Resistance in Clostridium difficile: Resistance Mechanisms and Antimicrobial Susceptibility Testing. Journal of Clinical Microbiology, 2017. 55(7): p. 1998-2008.

Teng, P., et al., Facilely accessible quinoline derivatives as potent antibacterial agents. Bioorganic & Medicinal Chemistry, 2018. 26(12): p. 3573-3579


Wang, Y., et al., TPL2 is a key regulator of intestinal inflammation in C. difficile infection. Infection and Immunity, 2018.


Chunhui, L., et al., Bis‐Cyclic Guanidines as a Novel Class of Compounds Potent against Clostridium difficile. ChemMedChem. 0(0).


Xu, D., et al., Bioprospecting Deep-Sea Actinobacteria for Novel Anti-infective Natural Products. Frontiers in Microbiology, 2018. 9: p. 787.


Zhu, D., J.A. Sorg, and X. Sun, Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection. Frontiers in Cellular and Infection Microbiology, 2018. 8: p. 29.


Zhao, S., et al., Immune-based treatment and prevention of Clostridium difficile infection. Human Vaccines & Immunotherapeutics, 2014. 10(12): p. 3522-3530.


Kim, H.B., et al., Beneficial Effect of Oral Tigecycline Treatment on Clostridium difficile Infection in Gnotobiotic Piglets. Antimicrobial Agents and Chemotherapy, 2014. 58(12): p. 7560-7564.


Ali, Y., et al., Temperate Streptococcus thermophilus phages expressing superinfection exclusion proteins of the Ltp type. Frontiers in Microbiology, 2014. 5: p. 98.


Kim H, B, Q, Zhang X, Sun G, Beamer D, Schmidt Y, Wang & S, Tzipori. Effect of oral tigecycline treatment on Clostridium difficile and human gut microflora. Antimicrob Agents Chemother.. 58(12) : 7560-4, 2014.


Zhang K, S, Martinod & X, Sun. Clostridium difficile infection in horses. Austin J Vet Sci & Anim Husb.. 1(1) : 5, 2014.


Zhao S, C, Ghose-Paul KS Zhang S, Tzipori and X, Sun. Clostridium difficile infection: virulence factors, adaptive immunity and vaccine development. Austin J Infect Dis.. 1(1) : 7, 2014.


Zhang J, X, Rui L, Wang Y, Guan X, Sun M, Dong. Polyphenolic extract from Rosa rugosa tea inhibits bacterial quorum sensing and biofilm formation. Food Control. 42: 125-131, 2014.


Wang Y, K, Q, Zou J, H, Sun H, A, Wang X, Sun Z, F, Chen Y, X, Yan. Screening of ssDNA aptamers against a zearalenone monoclonal antibody and development of a ssDNA-based enzyme-linked oligonucleotide assay for determination of zearalenone in corn. J Agric Food Chem.. , 2014.


Zhang H, W, Li X, Rui X, Sun M, Dong. Lactobacillus plantarum 70810 from Chinese paocai as a potential source of β-galactosidase for prebiotic galactooligosaccharides synthesis. Eur Food Res Technol. 236: 817-826, 2013.


Steele J, K, Chen X, Sun Y, Zhang H, Wang S, Tzipori & H, Feng. Toxemia is the cause of systemic disease in the piglet and mouse models of Clostridium difficile infection. J. Infect. Dis.. 205(3) : 384-91, 2012.


Wu J, Lu Z, Nie M, Zhou H, Sun X, Xue X, Bi J, Fang G. Optimization of cryopreservation procedures for porcine endothelial progenitor cells. Journal of Bioscience and Bioengineering. 113(1) : 117-23, 2012.


Steele J, Chen K, Sun X, Zhang Y, Wang H, Tzipori S, Feng H. Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models. The Journal of Infectious Diseases. 205(3) : 384-91, 2012.


Wang H, Sun X, Zhang Y, Li S, Chen K, Shi L, Nie W, Kumar R, Tzipori S, Wang J, Savidge T, Feng H. A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection. Infection and Immunity. 80(8) : 2678-88, 2012.


Sun X, Wang H, Zhang Y, Chen K, Davis B, Feng H. Mouse relapse model of Clostridium difficile infection. Infection and Immunity. 79(7) : 2856-64, 2011.

Sun X, Savidge T, Feng H. The enterotoxicity of Clostridium difficile toxins. Toxins. 2(7) : 1848-80, 2010.


Sun X, He X, Tzipori S, Gerhard R, Feng H. Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages. Microbial Pathogenesis. 46(6) : 298-305, 2009.


He X, Wang J, Steele J, Sun X, Nie W, Tzipori S, Feng H. An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins. Journal of Microbiological Methods. 78(1) : 97-100, 2009.


He X, Sun X, Wang J, Wang X, Zhang Q, Tzipori S, Feng H. Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A. Infection and Immunity. 77(6) : 2294-303, 2009.


Yang G, Zhou B, Wang J, He X, Sun X, Nie W, Tzipori S, Feng H. Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium. BMC Microbiology. 8: 192, 2008.


Sun X, Göhler A, Heller KJ, Neve H. The ltp gene of temperate Streptococcus thermophilus phage TP-J34 confers superinfection exclusion to Streptococcus thermophilus and Lactococcus lactis. Virology. 350(1) : 146-57, 2006.


Sun X, Mierke DF, Biswas T, Lee SY, Landy A, Radman-Livaja M. Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site. Molecular Cell. 24(4) : 569-80, 2006.


Past 2013






Schmidt, D.J., et al., A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection. Clinical and Vaccine Immunology : CVI, 2016. 23(9): p. 774-784.


Ghose, C., et al., Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC. Emerging Microbes & Infections, 2016. 5(2): p. e8.


Kim, H.B., Y. Wang, and X. Sun, A Detrimental Role of Immunosuppressive Drug, Dexamethasone, During Clostridium difficile Infection in Association with a Gastrointestinal Microbial Shift. Journal of microbiology and biotechnology, 2016. 26(3): p. 567-571.


Ghose, C., et al., Immunogenicity and Protective Efficacy of Clostridium difficile Spore Proteins. Anaerobe, 2016. 37: p. 85-95.