2016

Kim HB, Wang Y, Sun X. A Detrimental Role of Immunosuppressive Drug, Dexamethasone, During Clostridium difficile Infection in Association with a Gastrointestinal Microbial Shift. Journal of Microbiology and Biotechnology. 26(3) : 567-71, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26809802


Schmidt DJ, Beamer G, Tremblay JM, Steele JA, Kim HB, Wang Y, Debatis M, Sun X, Kashentseva EA, Dmitriev IP, Curiel DT, Shoemaker CB, Tzipori S. A Tetraspecific VHH-based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection. Clinical and Vaccine Immunology : CVI. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27413067


Ghose C, Eugenis I, Sun X, Edwards AN, McBride SM, Pride DT, Kelly CP, Ho DD. Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC. Emerging Microbes & Infections. 5: e8, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26839147


Ghose C, Eugenis I, Edwards AN, Sun X, McBride SM, Ho DD. Immunogenicity and protective efficacy of Clostridium difficile spore proteins. Anaerobe. 37: 85-95, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26688279


2015
Wang YK, Zou Q, Sun JH, Wang HA, Sun X, Chen ZF, Yan YX. Screening of single-stranded DNA (ssDNA) aptamers against a zearalenone monoclonal antibody and development of a ssDNA-based enzyme-linked oligonucleotide assay for determination of zearalenone in corn. Journal of Agricultural and Food Chemistry. 63(1) : 136-41, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25485848


Sponseller JK, Steele JA, Schmidt DJ, Kim HB, Beamer G, Sun X, Tzipori S. Hyperimmune bovine colostrum as a novel therapy to combat Clostridium difficile infection. The Journal of Infectious Diseases. 211(8) : 1334-41, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25381448


Huang T, Perez-Cordon G, Shi L, Li G, Sun X, Wang X, Wang J, Feng H. Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells. Pathogens and Disease. 73(3) , 2015. http://www.ncbi.nlm.nih.gov/pubmed/25743476


Wang YK, Yan YX, Kim HB, Ju X, Zhao S, Zhang K, Tzipori S, Sun X. A chimeric protein comprising the glucosyltransferase and cysteine proteinase domains of toxin B and the receptor binding domain of toxin A induces protective immunity against Clostridium difficile infection in mice and hamsters. Human Vaccines & Immunotherapeutics. 11(9) : 2215-22, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26036797


Zhang K, Zhao S, Wang Y, Zhu X, Shen H, Chen Y, Sun X. The non-toxigenic Clostridium difficile CD37 protects mice against infection with a BI/NAP1/027 type of C. difficile strain. Anaerobe. 36: 49-52, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26461425


Sun X, Hirota SA. The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection. Molecular Immunology. 63(2) : 193-202, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25242213


Yong Y, Liu S, Hua G, Jia R, Zhao Y, Sun X, Liao M, Ju X. Identification and functional characterization of Toll-like receptor 2-1 in geese. BMC Veterinary Research. 11: 108, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25967535


2014
Ali Y, Koberg S, Heßner S, Sun X, Rabe B, Back A, Neve H, Heller KJ. Temperate Streptococcus thermophilus phages expressing superinfection exclusion proteins of the Ltp type. Frontiers in Microbiology. 5: 98, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24659988


Kim HB, Zhang Q, Sun X, Beamer G, Wang Y, Tzipori S. Beneficial effect of oral tigecycline treatment on Clostridium difficile infection in gnotobiotic piglets. Antimicrobial Agents and Chemotherapy. 58(12) : 7560-4, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25267665


Zhao S, Ghose-Paul C, Zhang K, Tzipori S, Sun X. Immune-based treatment and prevention of Clostridium difficile infection. Human Vaccines & Immunotherapeutics. 10(12) : 3522-30, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25668664


Kim H, B, Q, Zhang X, Sun G, Beamer D, Schmidt Y, Wang & S, Tzipori. Effect of oral tigecycline treatment on Clostridium difficile and human gut microflora. Antimicrob Agents Chemother.. 58(12) : 7560-4, 2014.


Zhang K, S, Martinod & X, Sun. Clostridium difficile infection in horses. Austin J Vet Sci & Anim Husb.. 1(1) : 5, 2014.


Zhao S, C, Ghose-Paul KS Zhang S, Tzipori and X, Sun. Clostridium difficile infection: virulence factors, adaptive immunity and vaccine development. Austin J Infect Dis.. 1(1) : 7, 2014.


Zhang J, X, Rui L, Wang Y, Guan X, Sun M, Dong. Polyphenolic extract from Rosa rugosa tea inhibits bacterial quorum sensing and biofilm formation. Food Control. 42: 125-131, 2014.


Wang Y, K, Q, Zou J, H, Sun H, A, Wang X, Sun Z, F, Chen Y, X, Yan. Screening of ssDNA aptamers against a zearalenone monoclonal antibody and development of a ssDNA-based enzyme-linked oligonucleotide assay for determination of zearalenone in corn. J Agric Food Chem.. , 2014.


2013
Zhang H, W, Li X, Rui X, Sun M, Dong. Lactobacillus plantarum 70810 from Chinese paocai as a potential source of β-galactosidase for prebiotic galactooligosaccharides synthesis. Eur Food Res Technol. 236: 817-826, 2013.


past-2012
Steele J, K, Chen X, Sun Y, Zhang H, Wang S, Tzipori & H, Feng. Toxemia is the cause of systemic disease in the piglet and mouse models of Clostridium difficile infection. J. Infect. Dis.. 205(3) : 384-91, 2012.


Wu J, Lu Z, Nie M, Zhou H, Sun X, Xue X, Bi J, Fang G. Optimization of cryopreservation procedures for porcine endothelial progenitor cells. Journal of Bioscience and Bioengineering. 113(1) : 117-23, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22036230


Steele J, Chen K, Sun X, Zhang Y, Wang H, Tzipori S, Feng H. Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models. The Journal of Infectious Diseases. 205(3) : 384-91, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22147798


Wang H, Sun X, Zhang Y, Li S, Chen K, Shi L, Nie W, Kumar R, Tzipori S, Wang J, Savidge T, Feng H. A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection. Infection and Immunity. 80(8) : 2678-88, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22615245


Sun X, Wang H, Zhang Y, Chen K, Davis B, Feng H. Mouse relapse model of Clostridium difficile infection. Infection and Immunity. 79(7) : 2856-64, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21576341


Sun X, Savidge T, Feng H. The enterotoxicity of Clostridium difficile toxins. Toxins. 2(7) : 1848-80, 2010. http://www.ncbi.nlm.nih.gov/pubmed/22069662


Sun X, He X, Tzipori S, Gerhard R, Feng H. Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages. Microbial Pathogenesis. 46(6) : 298-305, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19324080


He X, Wang J, Steele J, Sun X, Nie W, Tzipori S, Feng H. An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins. Journal of Microbiological Methods. 78(1) : 97-100, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19393695


He X, Sun X, Wang J, Wang X, Zhang Q, Tzipori S, Feng H. Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A. Infection and Immunity. 77(6) : 2294-303, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19307220


Yang G, Zhou B, Wang J, He X, Sun X, Nie W, Tzipori S, Feng H. Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium. BMC Microbiology. 8: 192, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18990232


Sun X, Göhler A, Heller KJ, Neve H. The ltp gene of temperate Streptococcus thermophilus phage TP-J34 confers superinfection exclusion to Streptococcus thermophilus and Lactococcus lactis. Virology. 350(1) : 146-57, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16643978


Sun X, Mierke DF, Biswas T, Lee SY, Landy A, Radman-Livaja M. Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site. Molecular Cell. 24(4) : 569-80, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17114059

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